15 results
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - ... • Hypocalcemia/Late ... - Hypercalcemia ... • HAGMA • Late ... #nephrology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Dermatomyositis) AKI - Pathophysiology ... oxidative iniury Treatment ... Iinitial rate: 1 ... Dialysis for severe hyperkalemia ... Summary #causes #treatment
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... lysis syndrome - Rhabdomyolysis ... deficiency • Renal ... causes #potassium #high ... #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... lysis syndrome - Rhabdomyolysis ... deficiency • Renal ... causes #potassium #high ... #nephrology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... Spontaneous if high ... proliferation rate ... hydration - Hyperkalemia
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
Complications - Hypercalcemia ... of calcium in renal ... Glomerular filtration rate ... of abnormally high ... Hyperuricemia #Pathophysiology
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Glomerular Filtration Rate ... Creatinine • Chronic renal ... • NSAlDs #Hyperkalemia ... IntercellularShift #Nephrology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Collapse: • Pathophysiology ... Decreased pulse rate ... Liver injury, Rhabdomyolysis ... High body temperatures ... Hypocalcemia - Hyperkalemia
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
• Present in high ... Pneumocystis pneumonia (late ... > 1.5) with a sensitivity ... 94 and 84% Renal ... Muscle: • Rhabdomyolysis
Renal Replacement Therapy (RRT) - ICU One Pager Summary
Indications (AIEOU):
 • A: Acidosis (usually severe metabolic)
Renal Replacement ... derangements (hyperkalemia ... , hypercalcemia, ... High clearance achieved ... RRT #managment #nephrology