19 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
a Sickle Cell Crisis ... These cells can ... Crises can be precipitated ... The underlying pathophysiology ... #Features #Signs
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... • Langerhan cells ... hair follicles -> causes ... Manifestations #pathophysiology ... #diagnosis #signs
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... cerebritis #diagnosis #management
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
remainder likely arises ... Signs of immunodeficiency ... to produce all classes ... humoral immunity Signs ... Agammaglobulinemia #XLinked #pathophysiology
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... - Erosions and crusts ... erosions in ~20% Management
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
intoxication Cause ... - Gitelman SIGNS ... smooth muscle cells ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... symptoms are not caused ... skin (16-32%): lupus ... #Signs #Symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... Escorial criteria uses ... Lateral #Sclerosis #neurology ... #diagnosis #management
Avascular Necrosis: Pathogenesis and Clinical Findings
 • Physical Trauma (esp. to the scaphoid bone with damage
disease (sickle crisis ... ) • Multiple causes ... therapy - Lupus ... AvascularNecrosis #pathophysiology ... #diagnosis #signs
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
Bell's Palsy - Diagnosis ... ophthalmoplegia), systemic signs ... CNS inflammatory cause ... within 4m #Bells ... #Treatment #Neurology