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diagnosis management potassium treatment differential pharmacology binding cardiology comparison digoxin hyponatremia hypotonic k kdigo medications pathophysiology physiologic rhabdomyolysis sodium
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Mechanism: Exchanges calcium ... for K; also binds ... magnesium, and calcium ... patients sensitive to high ... #pharmacology #table
KDIGO Treatment algorithm for management of acute hyperkalemia in the emergency department • Place on cardiac
KDIGO Treatment algorithm ... lead ECG • IV calcium ... • Consider K+ binder ... treatment #potassium #high ... #nephrology #KDIGO
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pump - Digoxin works ... causes: - Increased ... - Hyperkalemia ( ... high potassium levels ... Because digoxin binds
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... fluid/Lactated ringers ... potassium and calcium ... per day until stable ... #treatment #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
reabsorption) Workup ... only if no clear cause ... Elimination (see Table ... Treatments: • Calcium ... Treatment #potassium #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... diuresis can be high ... : Hypovolemia, Hypervolemia ... differential #diagnosis #table ... #sodium #nephrology
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