107 results
Faget's Sign & Liebermeister's Rule
Pulse-Temperature Dissociation
EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM
INFECTIOUS
BPM INFECTIOUS CAUSES ... • Malaria • Leptospirosis ... OTHER CAUSES ... CLINICAL UTILITY ... #differential #causes
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
Leptospirosis Pathogen ... non-productive cough, nausea ... Epidemiologic exposure + clinical ... #Leptospira #microbiology ... #diagnosis #treatment
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Non-Infectious Causes ... disease • Behcet's syndrome ... • Hyper-IgD syndrome ... • Leptospirosis ... • Malaria • Leptospirosis
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
Infections BRASH Syndrome ... • Yellow fever ... Babesiosis • Leptospirosis ... Spondylarthropathies Other causes ... differential #diagnosis #causes
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
Cardiopulmonary Syndrome ... • Prodrome: fever ... • Autopsy PCR Treatment ... diagnosis #management #treatment ... #microbiology #
Lung Abscess
Microbiology:
 • Polymicrobial 
 • Anaerobes (most common) 
Clinical: 
 • Indolent symptoms that evolve
Lung Abscess Microbiology ... most common) Clinical ... to rnonths • Fever ... , hemoptysis Treatment ... Diagnosis #Pulmonary #Clinical
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
Fever vs Hyperthermia ... Fever: • Regulated ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... • Treatment:
Differential Diagnosis - Noninfectious Causes of Fever

CRITICAL DIAGNOSES:
 - Acute myocardial infarction
 - Pulmonary embolism or
Noninfectious Causes ... of Fever CRITICAL ... Neuroleptic malignant syndrome ... Postmyocardiotomy syndrome ... #Causes #Differential
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... Actively maintained fever ... CAUSES OF HYPERTHERMIA ... #Differential #Causes
Summary of Infections in which Steroids play a role in treatment
 • TB meningitis
 • TB
play a role in treatment ... pericarditis (select cases ... reconstitution inflammatory syndrome ... Severe typhoid fever ... • Ramsay Hunt syndrome