32 results
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
Leptospirosis Pathogen ... Epidemiologic exposure + clinical ... TheIDtrivia #Leptospirosis ... #Leptospira #microbiology ... #diagnosis #treatment
Lung Abscess
Microbiology:
 • Polymicrobial 
 • Anaerobes (most common) 
Clinical: 
 • Indolent symptoms that evolve
Lung Abscess Microbiology ... most common) Clinical ... to rnonths • Fever ... , hemoptysis Treatment ... Diagnosis #Pulmonary #Clinical
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... syndromes Clinical ... is the main clinical ... Treatment: • Corticosteroids ... #Rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... sequestration and activation ... explain symptoms • Fever ... : 33% • Treatment ... : No • Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly ... #summary #rheumatology
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome • Clinically ... Diagnosis and Treatment ... Algorithm Matthew ... Syndrome #HES #Hematology ... diagnosis #management #algorithm
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... Lutzomyia verrucarum Clinical ... coinfection, toxo reactivation ... Clinical Presentation ... TREATMENT: ​• Acute
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... following: • Fever ... • Bicytopenia Treatment ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... diagnosis #management #treatment ... #rheumatology
Giant Cell Arteritis (GCA) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Visual Symptoms/Loss or
Vasculitis Management Algorithm ... Symptoms/Loss or Critical ... Vasculitis #Management #Treatment ... ACR2021 #Guidelines #algorithm ... #rheumatology