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diagnosis differential causes lung management chronic diseases dyspnea organizing amiodarone boop comparison eosinophilia eosinophilic induced interstitial nonresolving returning sob table
Cryptogenic Organizing Pneumonia (COP) Cryptogenic Organizing Pneumonia Overview: • Idiopathic form of organizing pneumonia • formerly BOOP
Pneumonia (COP) ... cough, dyspnea, fever ... , Pulmonary lymphoma ... #COP #BOOP #pulmonary ... #ILD #diagnosis
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
• Idiopathic pulmonary ... (NSIP), Cryptogenic ... (COP), Respiratory ... (DIP), Acute interstitial ... : Acute, Chronic
Non-Resolving Pneumonias: Etiologies Unusual Infections: - Immunocompromised patients (e.g.: Mycobacterium, Aspergillosis, Nocardia) - Endemic Fungi (e.g.: Histoplasmosis,
psittaci/avian, leptospirosis ... yersinia/rats, Q fever ... ) - Returning travelers ... Eosinophilic PNA (acute ... - Cryptogenic
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Travelers from ... , acute HIV infection ... Cough, dyspnea - Pneumonia ... melioidosis, typhoid, pulmonary ... , Lassa fever, acute
Cryptogenic Organizing Pneumonia - Illness Script PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Cryptogenic Organizing ... /SYMPTOMS: • Acute ... Cough, dyspnea, fever ... TylerLarsenMD #COP ... #management #pulmonary
Approach to Eosinophilic Lung Diseases • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
Lung Diseases • Acute ... Eosinophilic Pneumonia ... Fungal, parasites; Travel ... similar to AEP or CEP ... Lung #Diseases #pulmonary
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm Pericardial • Effusion • Cardiac Tamponade* • Constriction Myocardial •
Stable Angina • Acute ... • Asthma • COPD ... Alveoli • Pneumonia ... • ARDS • COPD ... Interstitium • ILD
Acute and Chronic Causes of Dyspnea - Differential Diagnosis Pulmonary/Chest Wall: • Acute: Trauma, COPD exacerbation, Asthma
Asthma attack, ILD ... Pleural effusion, Pneumonia ... Chronic: Asthma, COPD ... , CTEPH, ILD, Sarcoid ... poisoning, DKA, Fever
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
pleural effusions • Acute ... toxicity (e.g., acute ... Fever 4. ... Exclusion of other ILDs ... LDH • ↑ ESR, CRP
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