44 results
Causes of B12 deficiency. 

This great diagram shows normal absorption and outlines most possible causes. At
Causes of B12 deficiency ... most possible causes ... the top is a B12-deficient ... the stomach and travels ... #Diagnosis #Pathophysiology
Vitamin deficiency causes clinical disease
Vitamin C deficiency causes scurvy.  Vitamin C is important for the
Vitamin deficiency ... causes clinical ... causes scurvy. ... causes failure ... #Pathophysiology
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
lysosomal acid lipase deficiency ... triglycerides, a deficiency ... and gut, which causes ... #clincial #peds ... NEJM #Wolmans #radiology
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... → Inflammation causes ... endpoint of all-cause ... diagnosis #management #cardiology
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
Leptospirosis Pathogen ... non-productive cough, nausea ... Disease: Jaundice + renal ... Epidemiologic exposure + clinical ... TheIDtrivia #Leptospirosis
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
21-Hydroxylase Deficiency ... Pathogenesis and Clinical ... enzyme 21-OHase causes ... 21-OHD in the adrenal ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Tree in Bud Sign
The Tree-in-Bud sign represents Endobronchial spread in a linear branching pattern and centrilobular
It is caused by ... actually seen in all causes ... Sign #diagnosis #clinical ... #radiology #ChestCT ... #pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... • Vitamin C deficiency ... collection with EDTA Pathophysiology ... Phosphatase: • Other causes
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency ... Framework and Clinical ... Manifestations Causes ... of Thiamine Deficiency ... beriberi #nutrition #pathophysiology
Hypoglycemia - Differential Diagnosis Algorithm
Fasting Hypoglycemia:
 • Excess Insulin
 • Medications (e.g. Insulin Secretagogues, ß-Adrenergic Antagonists,
Idiopathic Other Causes ... : • Critical Illness ... Hypopituitarism • Adrenal ... Catecholamine Deficiency ... endocrinology #causes