73 results
Travel History - Clues to Infectious Disease Diagnosis in a Traveler 
 • Where did you
Clues to Infectious ... Disease Diagnosis ... rural → Geographic disease ... → Leptospirosis ... #differential #Diagnosis
Vitamin deficiency causes clinical disease
Vitamin C deficiency causes scurvy.  Vitamin C is important for the
Vitamin deficiency ... causes clinical ... disease Vitamin ... C deficiency causes ... #Pathophysiology
Causes of B12 deficiency. 

This great diagram shows normal absorption and outlines most possible causes. At
Causes of B12 deficiency ... most possible causes ... the top is a B12-deficient ... the stomach and travels ... #Diagnosis #Pathophysiology
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
Leptospirosis Pathogen ... non-productive cough, nausea ... ARDS Diagnosis ... Epidemiologic exposure + clinical ... #microbiology #diagnosis
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... → Inflammation causes ... endpoint of all-cause ... #management #cardiology
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
- Differential Diagnosis ... DAT (-) → G6PD Deficiency ... malignancy, autoimmune disease ... HTN) • Recent travel ... #Algorithm #causes
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease ... Pathophsiology ... storage disorder • Deficiency ... in GBA1 gene Clinical ... #Diagnosis #Signs
High Output Heart Failure - Pathophysiology and Differential Diagnosis
Obesity - Systemic Vasodilation, Vasoactive Adipokines
Arteriovenous Fistula -
Heart Failure - Pathophysiology ... and Differential Diagnosis ... Vasodilation Lung Disease ... #Differential #Diagnosis ... #cardiology #causes
Causes of Wide Pulse Pressure - Differential Diagnosis
Physiologic:
 • Advanced age-arteriosclerosis (less compliant arteries)
 • Well
Causes of Wide Pulse ... - Differential Diagnosis ... - Severe iron deficiency ... Chronic pulmonary diseases ... #causes #cardiology
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
confirmed the diagnosis ... , or Wolman’s disease ... and gut, which causes ... #clincial #peds ... NEJM #Wolmans #radiology