11 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis (MS ... nearly 3:1 • MS ... • Or brainstem syndromes ... criteria for MS ... (Spinal cord predominant
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... Syndrome ->Cord ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics
Lesions of the Spinal cord - Spinal Cord Syndromes

Spinal cord lesions can result in permanent neurologic
- Spinal Cord Syndromes ... Lower motor neuron symptoms ... Upper motor neuron symptoms ... Vertebral burst fracture ... #differential #diagnosis
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... Transverse Myelitis - Clinical ... swollen, while in MS ... Predictive of MS ... Multiple sclerosis (MS
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal Cord ... Demyelinating Disease (MS ... Guillain-Barre syndrome ... heavy metals), Critical ... #differential #diagnosis
Principal patterns of loss of sensation.
 (a) Thalamic lesion: sensory loss throughout opposite side (rare).
(c) Central cord ... Brown—Séquard syndrome ... MS: loss of proprioception ... #Diagnosis #Neurology ... Comprehensive Review in Clinical
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... neurological lesion: Clinical ... compression by fractured ... MCTD, Sjogren syndrome ... spinalcord #disorders #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Syndrome ... Viral Infection Clinical ... symptoms - most ... hemolytic #anemia #hematology ... #diagnosis
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Visual or auditory symptoms ... conjunction with symptoms ... important, as early diagnosis ... MRI lesions and clinical ... consistent with MS
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... matter, spinal cord ... (Clinical Dx). ... #signs #symptoms ... #rheumatology #