10 results
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
) Differential Diagnosis ... Irreversible-biopsy required • Lupus ... • Discoid lupus ... #Diagnosis #Algorithm ... #causes
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
Diagnosis Framework ... Localized / Focal ... Disease: Discoid lupus ... : Lupus erythematosus ... Examination: • Signs
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
SLE) - Typical Signs ... /Symptoms Alopecia ... Arthralgia / arthritis, Myositis ... #Symptoms #diagnosis ... #rheumatology
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
areas -> Scaring alopecia ... hair follicles -> causes ... cells -> Incr local ... pathophysiology #diagnosis ... #signs #symptoms
Focal / Localized Hair Loss (Alopecia) - Differential Diagnosis Algorithm

Scarring - Irreversible-biopsy required
 - Infectious
Focal / Localized ... - Differential Diagnosis ... • Discoid lupus ... #Focal #Localized ... #causes
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Photosensitivity, Alopecia ... Positive in 60-80% of cases ... Erythematosus #Diagnosis ... #rheumatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Overview Focal ... • Bilateral signs ... • Infectious causes ... Mycoplasma - Leptospirosis ... #diagnosis #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Photosensitivity, Alopecia ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... B-cell activity → local ... symptoms are not caused ... skin (16-32%): lupus ... #Management #Signs
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
lacrimal glands: • Focal ... Hypocomplementemia • Can cause ... neuropathy, transverse myelitis ... Nephrogenic DI Hematologic ... #Diagnosis #Management