12 results
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... Diagnosis: • Pancytopenia ... if neutropenic fever ... #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion
Classic lab findings in HLH: ↑↑ ferritin, Anemia,
Clinical Features: Fever ... : ↑↑ ferritin, Anemia ... ): Molecular diagnosis ... : • Fever • Splenomegaly ... #hematology #criteria
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... Presentation: • Fever ... recurrent infections/fevers ... #oncology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
- Nonremitting fever ... with leukopenia, anemia ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
) B symptoms → fevers ... 5) Symptoms of anemia ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... Criteria: • Elevated ... present, symptoms, signs ... #Management #Summary ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... Diagnosis via genetic ... following: • Fever ... #management #treatment ... #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
m/s • Other signs ... for definitive diagnosis ... Diagnostic criteria ... #Hypertension #diagnosis ... #management #hepatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... • Neutropenia, anemia ... workup #oncology #hematology