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rheumatology differential classification msk arthritis dermatology leukemia management pain vasculitis workup antimda5 antimda5dm approach chronic dermatomyositis effusions erythematosus eularacr hodgkins
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Headaches, bone pain, fever ... , joint pain, bleeding ... #Leukemia #Hematology ... #Oncology #Diagnosis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... acute rheumatic fever ... Like in this case ... Chronic = RA, SLE ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Lymphadenopathy • Fevers ... Physical Exam/Signs ... #workup #oncology ... #hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Constitutional domain: Fever ... in at least 2 joints ... pericarditis • Hematologic ... #SLE #Systemic ... Erythematosus #diagnosis
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... - Differential Diagnosis ... Fever/Chills/Joint ... arthritis - SLE ... Acute rheumatic fever
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and pain of the joints ... Causes: - Idiopathic ... , breast CA - Hematologic ... #dermatology #oncology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... weeks) Can Be Caused ... • Rheumatic fever ... arthritis • SLE
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
chest (in a V-sign ... interphalangeal joints ... Dermatomyositis • Fever ... CD4+ and CD8+ T cell ... #dermatology #diagnosis
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • Dyspnea • Fever ... through Ann Arbor criteria ... classification #hematology ... #oncology #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... purpura: Strong sign ... tract, and often causes ... Palpable purpura, joint ... #Rheumatology
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