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differential rheumatology management classification arthritis infections joint msk oncology pain vasculitis approach chronic cll dengue fuo hemophagocytic history hlh hpi
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... thin smear • Signs ... values supporting hematologic ... UnknownOrigin #workup ... #diagnosis
Travel History - Clues to Infectious Disease Diagnosis in a Traveler • Where did you
Clues to Infectious ... Disease Diagnosis ... → Leptospirosis ... Rabies, cat scratch fever ... Commercial sex worker
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Lymphoma Workup ... through Ann Arbor criteria ... #lymphoma #diagnosis ... classification #hematology
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Non-Infectious Causes ... • Leptospirosis ... 1-2 weeks • Hodgkin ... Brucellosis Faget's Sign
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphoma SLL ... Lymphadenopathy • Fevers ... Physical Exam/Signs ... #workup #oncology ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Hemopathies+++: Hodgkin ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... treatment #summary #rheumatology
Modified dengue severity classification, PAHO/WHO Dengue without warning signs - DNWS: • Person who lives or has
who lives or has traveled ... days and presents fever ... the following criteria ... organs #dengue #fever ... classification #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... weeks) Can Be Caused ... • Rheumatic fever ... arthritis • SLE
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Criteria: • Sensory ... • Bilateral signs ... Evaluate for NMO, SLE ... Mycoplasma - Leptospirosis ... Disorders: - SLE
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
to Joint Pain - Diagnostic ... acute rheumatic fever ... Like in this case ... Chronic = RA, SLE ... #approach #workup
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