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oncology treatment chronic cll hemeonc hemophagocytic hlh leukemia lymphocytic lymphohistiocytosis anemia aplastic arteritis classification differential fuo gca giantcell hodgkins leukostasis
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... • CNS symptoms ... thin smear • Signs ... values supporting hematologic ... #diagnosis
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Frequent Differential Diagnoses ... infection Cardinal Symptoms ... localizing signs ... or symptoms - Malaria ... #differential #diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... if neutropenic fever ... ) Complications: ... #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... Summary Diagnostic ... , signs, and complications ... #Management #Summary ... #treatment #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Lymphadenopathy • Fevers ... Physical Exam/Signs ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
→ fevers, night ... thrombocytopenia Complications ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... - 80% have fever ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... symptoms can mimic ... following: • Fever ... #management #treatment ... #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
and ophthalmic complications ... systemic sx + signs ... GCA #Temporal #Signs ... #Symptoms #Diagnosis ... #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... ingestion • B symptoms ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management
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