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rheumatology differential management neurology biliary hepatology pbc primary scleroderma vasculitis workup algorithm als amyotrophic ana antibodies antinuclear autoantibodies cholangitis classification
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Systemic Sclerosis ... @AnnKumfer #Systemic ... #Sclerosis #Scleroderma ... #diagnosis #signs ... #symptoms #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... skin thickening Signs ... and Symptoms: ... #SSc #rheumatology ... #diagnosis #signs
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary Cirrhosis ... Symptoms: Fatigue ... quadrant discomfort Signs ... PBC if 2/3 criteria ... #hepatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... sclerosis/scleroderma ... Primary Biliary Cirrhosis ... ANA #patterns #rheumatology ... #diagnosis #differential
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
central nervous system ... Diagnosis - Based ... Signs and symptoms ... criteria for MS ... #diagnosis #management
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... malignancies, Multiple sclerosis ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... failure PBC Signs ... and Symptoms: ... cholestasis, Primary sclerosis ... #workup #hepatology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Amyotrophic Lateral Sclerosis ... of the nervous system ... fasciculations Common Symptoms ... : months - Criteria ... : El Escorial criteria
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
conidia → Yeast → travel ... Pericarditis • Sclerosing ... acute pulmonary, systemic ... , neutropenia, cirrhosis ... the circulatory system
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Symptoms (Sx) in ... , particularly scleritis ... purpura: strong sign ... #rheumatology #
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