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differential management oncology rheumatology causes algorithm rash secondary clinical hemeonc leukemia photo skinrash systemic allergy alopecia cancer generalized hairloss hemophagocytic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Hepatomegaly • Skin ... Diagnosis: • ... microglobulin Treatment ... workup #oncology #hematology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Dermatomyositis Erythema chronicum ... Antiphospholipid-antibody syndrome ... Sarcoidosis #dermatology ... #differential #diagnosis ... #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic ... #Algorithm #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential Diagnosis ... hemorrhage) • Chronic ... Myelodysplastic syndrome ... myeloid leukemia (CML ... #Causes #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Allogeneic stem cell ... only curative treatment ... #Management #treatment ... #hematology #oncology
Central Distribution, Febrile / Ill: - Viral Exanthem - Lyme Disease (erythema migrans) Central Distribution,
Afebrile, non-ill ... Stevens-Johnson Syndrome ... Afebrile / non-ill ... Rash #Algorithm #Diagnosis ... #Dermatology #Skin
Ulcerative Blastomycosis Skin Lesion 57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
Blastomycosis Skin ... Denies any travel ... Diagnosis? ... ca, squamous cell ... Blastomycosis #SkinRash #dermatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Generalized Differential Diagnosis ... Creatinine & BUN: • Chronic ... Myelodisplastic syndrome ... #generalized #dermatology ... #Differential #Diagnosis
Approach to the Rash in a an oncology patient - MINT-C Mnemonic M - Malignancy: Leukemia cutis,
Dermatoses: Sweet Syndrome ... Gangrenosum, NEH T - Treatment ... dermatoses #skin ... #differential #diagnosis ... MINTC #Mnemonic #dermatology
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