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hepatology management liver differential algorithm hbv lfts transaminitis dili hepatitis hepbv phases aclf acute aih anemia aplastic autoimmune behcet chemistry
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Drug-Induced Liver Injury ... #gastroenterology ... #management #diagnosis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... 5-10x normal - Chronic ... Patterns #Liver #Injury ... #hepatology #LFTs ... #differential #diagnosis
Hepatitis B Phases and Treatment Phase 1 - HBeAg+ Chronic Infection Phase 2 - HBeAg+ Chronic Hepatitis Phase 3
Hepatitis B Phases ... and Treatment ... HepBV #Phases #Treatment ... #Management #diagnosis ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... e.g. ascites), Chronic ... hepatitis fibrosis ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
- Differential Diagnosis ... Cirrhosis • Chronic ... Viral Hepatitis ... Drug-induced liver injury ... #hepatology #transaminitis
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Chronic Hepatitis ... B - Diagnosis and ... Chronic Hepatitis ... #Management #Treatment ... #Hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... #differential #Diagnosis ... #algorithm #gastroenterology ... #hepatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... - Symptoms of chronic ... pattern of liver injury ... regarding need for treatment ... #Management #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... > 2 • NASH, Chronic ... : > 3 • Chronic ... #diagnosis #algorithm ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
> 2 • NASH, Chronic ... viral hepatitis ... : > 3 • Chronic ... liver #chemistry #diagnosis ... #differential #Hepatology
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