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management aclf acute anemia aspergillus autoimmune betadglucan biomarkers chronic cirrhosis emergencies failure galactomannan hemeonc hemolytic hepatology infections infectiousdiseases liver mycoses
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Warm vs Cold Autoimmune ... Spherocytes • Treatment ... transient hemolysis • Treatment ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
in those with CLD ... months without treatment ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... infection (IFI) in hematologic ... concurrent admin of mold-active ... Galactomannan #diagnosis ... #comparison
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
conidia → Yeast → travel ... : • Direct fungal ... that exists as a mold ... arthroconidia; the fungus ... InfectiousDiseases #Fungal
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
> 4 days → add fungal ... syndrome): - Hematologic ... replacement Cord ... → no immediate treatment ... Oncology #HemeOnc #Diagnosis
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