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diagnosis management hematology msk neurology oncology posterior signs abdominal aids alzheimersdisease ammonia ankle associated causes clinical differentiation disorder encephalopathy fever
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential
Meralgia paresthetica: Pathogenesis and Clinical Findings Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica •
paresthetica • Symptoms ... 3-6 months of symptom ... lateral inguinal ligament ... MeralgiaParesthetica #MSK #pathophysiology ... #differential #
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
mutations - Down syndrome ... chromosome 21) Signs / Symptoms ... AlzheimersDisease #Dementia ... #pathophysiology ... diagnosis #signs #symptoms
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
impairment • HIV dementia ... Pathophysiology ... • Depressive symptoms ... The clinical syndrome ... neurocognitive #disorder #dementia
Posterior Ankle Impingement (Os Trigonum) Syndrome - MSK Radiology Imaging Findings: • Os trigonum which has marrow
(Os Trigonum) Syndrome ... hallucis longus Differential ... Posterior syndesmotic ligament ... findings and torn ligament ... flexion but no symptoms
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
myeloma, CML, AML ... rare): - Reye syndrome ... deficiency #Ammonia #Pathophysiology ... Hyperammonemia #Differential
Rare Causes of Abdominal Pain • Hereditary Angioneurotic Edema - Recurrent visceral that may by swelling
- May involve symptoms ... neuropsychiatric symptoms ... Median arcuate ligament ... syndrome - Pain ... Abdominal #Pain #differential
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Refeeding Syndrome ... overload) Other Symptoms ... • Nephrotic syndrome ... #Nutrition #Differential ... #Diagnosis #Pathophysiology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... age 70 years Symptoms ... transformation to AML ... blood count with differential ... progression to AML
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Encephalopathy Syndrome ... Clinico-Radiological Syndrome ... Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential
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