6 results
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
100% Hepatic, 0% Renal ... 75% Hepatic, 25% Renal ... 20% Hepatic, 80% Renal ... NOAC #Metabolism #Pharmacology ... #anticoagulation
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Monitoring - Renal ... - Resume #Oral ... #Anticoagulation ... Management #Table #Pharmacology
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
• Once a day oral ... coagulopathy - LMWH • Renal ... decisionaid #vte #anticoagulation ... #pharmacology
Heparin - Unfractionated Heparin (UFH) vs Low-Molecular-Weight Heparin (LMWH)
UFH:
 • Advantages: 
    -
clearance - Anticoagulation ... monitored - Ok in renal ... contraindicated in renal ... LMWH #Heparin #comparison ... Unfractionated #pharmacology
Xa Inhibitors - Apixaban and Rivaroxaban 
Oral Xa inhibitors are recommended by CHEST as first-line for
Rivaroxaban Oral ... Fibrillation requiring anticoagulation ... patients with normal renal ... Rivaroxaban #Dosing #Pharmacology
Adrenoceptor Actions
α1
 • Vascular smooth muscle - Contraction
 • Genitourinary smooth muscle - Contraction
 • Intestinal
Adrenoceptor Actions ... conduction velocity • Renal ... Lipolysis #Adrenoceptor ... receptors #actions #pharmacology ... pathophysiology #comparison