6 results
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... → Increased urine ... SaltWasting #SIADH #Pathophysiology ... diagnosis #nephrology #hyponatremia
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
non-arousable, decr urine ... #21HydroxylaseDeficiency #21OHD ... #pathophysiology ... #genetics #endocrinology
SGLT2 Inhibitors 
SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
glucose in the urine ... excretion in the urine ... SGLT2 #Inhibitors #Pharmacology ... DM2 #Diabetes #Endocrinology
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
The last step in purine ... Homeostasis #Gout #Pathophysiology ... #Pharmacology #
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
renal function/urine ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
is decreased), hypernatremia ... ↑ 24-hour urine ... signs #symptoms #endocrinology