22 results
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
– symptoms and signs ... , Dry coarse skin ... , Deafness Signs ... Goitre), Dry skin ... #PhysicalExam #Endocrinology
Cushing Syndrome - Signs and Symptoms
Generalized: Weight gain, Slow healing of cuts, Increased risk of infections,
Cushing Syndrome - Signs ... Muscular: Weakness Skin ... Cushings #Syndrome #Signs ... Symptoms #diagnosis #endocrinology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
LcSSc) - distal skin ... thickening Signs ... changes): skin ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Hypothyroidism and Hyperthyroidism - Symptoms and Signs
Hypothyroidism:
 - General - From asymptomatic to myxedema coma, “Like
- Symptoms and Signs ... Menorrhagia - Skin ... • Skin is ... Hyperthyroid #Symptoms #Signs ... #Diagnosis #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... tunnel, OSA, Incr skin ... #FeedbackLoop #endocrinology
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
Hydroxylase Deficiency - Signs ... gonadal failure • Skin ... Hydroxylase #Deficiency #Signs ... Symptoms #diagnosis #endocrinology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
vomiting • Fatigue Signs ... Reduced libido • Signs ... patches on the skin ... addisons #disease #endocrinology ... #diagnosis #signs
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... cold & mottled skin ... pathophysiology #genetics #endocrinology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
organ-specific signs ... symptoms (eg, skin ... Differential #diagnosis #hematology