8 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
myalgias, HoTN, edema ... common • Imaging: CXR ... - pulmonary opacities ... Diagnosis: Infection ... #hematology #oncology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Hemoptysis, Peripheral edema ... Diagnosis for Pulmonary ... allopurinol), Infection ... anti-ANCA ab, anti-GBM ... , anti-CCP • CXR
ARDS/VALI progression over the course of 1 week 
 (a) Day 1 - No pathological findings.
consolidations in lower lobes ... structures help in the differential ... diagnosis of pulmonary ... #Clinical #Radiology ... #CXR #ChestXRay
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... should be based on clinical ... Inferomedial temporal lobes ... + mass effect/Edema ... #differential #
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... Infectious: Mycoplasma ... Coxsackie, CMV, EBV ... hepatitis • Pulmonary
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
of right middle lobe ... Hematologic malignancy ... Disease: Clinical ... Lung Disease: • Clinical ... #differential #
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
noncompliance • Clinical ... initiation Clinical ... leukoencephalopathy (PML ... and peripheral edema ... Leishmaniasis Differential
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... infection • Family ... Hodgkin Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... classification #hematology