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cardiology management hfref heartfailure pharmacology guideline ckd congestive diagnosis failure heart schf treatment accaha acei algorithm angiotensinreceptorblockers angiotensinreceptorneprilysininhibitor arb bumetanide
Guidelines Directed medical therapy for Heart Failure Satyendra Dhar, MD, @DharSaty #HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
DharSaty #HFrEF #GDMT ... angiotensinreceptorblockers #ARB #ARNI ... #PARADIGM-HF #EMPEROR-Reduced ... MineralocorticoidReceptorAntagonist #LoopDiuretic
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies •
Approach: ACE, ARB, ARNI ... -2 Inhibitor → ARNI ... Heart #Failure #CHF ... Guideline #management #GDMT
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy • Beta-blocker • ACE,
• ACE, ARB, ARNI ... Heart #Failure #CHF ... Guideline #management #GDMT
HFrEF: Guideline Directed Medical Therapy "Must Be On" • ACEI, ARB, or ARNI AND select Beta Blockers
ACEI, ARB, or ARNI ... ACEI or ARB • ARNI ... #medications #chf ... #cardiology #GDMT
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD EMPA-REG OUTCOME - Empagliflozin lowered CV events
for SGLT2i in HF ... for SGLT2i in HF ... improved HF outcomes ... in HFrEF on GDMT ... outcomes in HFrEF on GDMT
Stages in the development of HF and recommended therapy by stage. ACEI indicates angiotensin-converting enzyme inhibitor;
development of HF ... ejection fraction; GDMT ... medical therapy; HF ... #CHF #Congestive
Heart Failure (HFrEF) Treatment - GDMT for stage C For patients with Heart Failure with REDUCED
HFrEF) Treatment - GDMT ... Medical Therapy (GDMT ... GDMT is basically ... /ambcarerx #CHF ... #sCHF #HeartFailure
Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD • Class I pillars of HFrEF GDMT across
Medical Therapy (GDMT ... pillars of HFrEF GDMT ... disease: ACEI, ARB, ARNI ... after core GDMT ... part of HFrEF GDMT
Heart failure with Reduced Ejection Fraction (HFrEF) Clinical Presentation 1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
81% for acute HF ... 5 pts w/ acute HF ... Inhibitors and ARBs • ARNIs ... #pharmacology #sCHF
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
May have typical HF ... Avoid ARB/ACE-I/ARNI ... pregnancy, teratogenic GDMT
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