23 results
Guidelines Directed medical therapy for Heart Failure 

Satyendra Dhar, MD, @DharSaty

#HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
DharSaty #HFrEF #GDMT ... AngiotensinReceptorNeprilysinInhibitor #ACEi ... MineralocorticoidReceptorAntagonist #LoopDiuretic
ACEI Antihypertensive Dose Comparison. Consider divided (BID) regimen for better pre-dose (trough) BP control for the
ACEI Antihypertensive ... the following ACEIs ... Monitor BP, potassium ... #ACEInhibitor #ACEIs
HFrEF: Guideline Directed Medical Therapy

"Must Be On"
 • ACEI, ARB, or ARNI AND select Beta Blockers
Must Be On" • ACEI ... before increasing ACEI ... Reducing: • ACEI ... chf #cardiology #GDMT
Heart Failure (HFrEF) Treatment - GDMT for stage C 

For patients with Heart Failure with REDUCED
HFrEF) Treatment - GDMT ... Medical Therapy (GDMT ... GDMT is basically ... initiate them on ACEI ... maximally tolerated ACEI
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy
 • Beta-blocker
 • ACE,
Beta-blocker • ACE ... Guideline #management #GDMT
Heart Failure with Reduced Ejection Fraction (HFrEF) - Guideline Directed Medical Therapy - Initiation Strategies

 •
Stepwise Approach: ACE ... Guideline #management #GDMT
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
binding to sodium–potassium–chloride ... Pathophysiology #Nephro #IM #LoopDiuretic
Stages in the development of HF and recommended therapy by stage. ACEI indicates angiotensin-converting enzyme inhibitor;
ACEI indicates angiotensin-converting ... ejection fraction; GDMT
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Aldosterone Release: ACE ... Pharmacology #Impaired #Potassium
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
with excreting potassium ... classes (Aliskiren, ACEI ... while retaining potassium ... will increase potassium ... , which is why potassium