2067 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... -> Uric Acid (low ... Urate Nephropathy (low ... Syndrome #TLS #Pathophysiology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Insufficiency - Pathophysiology ... aldosterone will be low ... Low ACTH leads to ... stimulation, thus low ... Insufficiency #Pathophysiology
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
cardiac output) - Low ... SvO2 → Low PaO2 ... COHb, MetHb) - Low ... CaO2 → Low SvO2 ... diagnosis #causes #pathophysiology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
NH4+ (relatively low ... ammonia #hepatology #pathophysiology
Hypothermia in Sepsis - Pathophysiology
 • 20% of septic pts → HYPOTHERMIA
 • Increased mortality 62%
Hypothermia in Sepsis - Pathophysiology ... hypothermia in sepsis: Low ... Hypothermia #sepsis #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
causes #potassium #low ... #pathophysiology
Renin-Angiotensin-Aldosterone System (RAAS) 

The kidneys produce renin in response to low blood pressure or low plasma
in response to low ... blood pressure or low ... #Pathophysiology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
common in young and low ... Osteoporosis -> Low ... weakened femur (e. g. low ... differential #causes #pathophysiology
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
• Decr TFPI Low ... Clot #Cirrhosis #Pathophysiology
Lipoprotein Metabolism

Enterocytes release absorbed lipids the form of triglyceride-rich chylomicrons. These are acted upon by endothelial
synthesize very-low-density ... The low density ... Cholesterol #Metabolism #Pathophysiology