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neurology rheumatology radiology algorithm aspergillus autoimmune betadglucan biomarkers brain causes cavitary compylobacterjejuni disease enhancing erythematosus flaccidpalsy fungal galactomannan gbs guillainbarresyndrome
CNS Ring-Enhancing Lesions - Differential Diagnosis • Infections: Cerebral abscess (bacterial, fungal, parasitic), Neurocysticercosis, Tuberculoma, Cerebral
Lesions - Differential ... Diagnosis • Infections ... • Malignancy: ... Metastases (lung ... #Differential #
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
Chorioretinitis • Diagnosis ... with lung nodules ... Neurocysticercosis Malignancy ... #Brain #differential ... #diagnosis #causes
Cavitary Lung Disease - Differential Diagnosis and Workup Algorithm Acute / Subacute: • Acute Infections: Lung abscess,
- Differential ... Diagnosis and Workup ... Parasitic, Viral • Malignancy ... #Disease #Diagnosis ... #Algorithm #lesion
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Diagnosis Framework ... • Neoplastic: Malignancy-associated ... dystrophies Work ... #Diagnosis #neurology
Guillain–Barré syndrome (GBS) (aka: Landry–Guillain–Barré–Strohl syndrome:  Most common cause of acute flaccid paralysis  Rapidly progressive ascending paralysis & areflexia  Autonomic
Differential diagnosis ... Multiple Sclerosis: CNS ... hyperreflexia, multiple lesions ...  Transverse myelitis ... relapses, requires long-term
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
papulosquamous lesions ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Infections • Malignancy ... and CNS • Headache
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... Conjunctivitis, mucositis ... exposure or Dx of malignancy ... chorioretinitis, CNS
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
in hematologic malignancy ... BAL GM does not differentiate ... Clav (may be + as long ... Galactomannan #diagnosis ... #comparison
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Anti-Mi2 (skin lesions ... disease Malignancy ... dermatomyositis) Malignancy ... #rheumatology #differential
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