8 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... Osmotic agents (mannitol ... urearetics) 3) Loop ... Adenosine #Nephron ... #Pathophysiology
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Acting on the Nephron ... (e.g. mannitol) ... 3) Loop Diuretics ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... loss through the nephron ... ), Isosorbide, Mannitol ... Pharmacology #nephrology #conversion ... #classes
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... acid and most diuretics ... limb of Henle's loop ... #Pathophysiology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Differential Diagnosis Algorithm ... Vomiting • NG suction ... tubular transport • Diuretics ... (loop/thiazide) ... Differential #Diagnosis #Algorithm
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... Remote use of loop ... or thiazide diuretics ... Vomiting/nasogastric suction ... #causes #urinary
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... Remote use of loop ... or thiazide diuretics ... pressure: Active diuretic ... the indicated causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Differential Diagnosis Algorithm ... Vomiting • NG suction ... contracted • Loop ... diuretics / Bartter's ... syndrome • Thiazide diuretics