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differential hematology management abnormal algorithm coagulation prolonged pt treatment workup amyloid cardiology cardiomyopathy challenges chest comparison criticalcare fluid hypercoagulable pain
Chest Pain - Diagnosis and Workup Algorithm History and Exam Acute life-threatening causes: • Acute myocardial infarction •
life-threatening causes ... Pulmonary embolism • Cardiac ... Initial workup: • EKG ... • Bedside ultrasound ... LET, lipase, PT. aPTT
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Prolonged Activated Partial ... . direct thrombin ... with systemic amyloidosis ... #diagnosis #differential
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... the PT and the aPTT ... . direct thrombin ... with systemic amyloidosis ... #diagnosis #differential
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
LVH, low-voltage EKG ... Testing: • EKG ... • Echocardiogram ... disproportionate atrial ... spleen • Fecal fat measurements
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
thromboembolism → Cardiac ... rhythm monitoring, Echocardiogram ... • Provoked (e.g ... screening, CBC, aPTT ... Workup #hematology #diagnosis
Fluid Responsiveness and Fluid Tolerance Testing - OnePager Summary Fluid resuscitation can be beneficial when required or
Arterial Line: ... Thermodilution measurement ... Point of Care Ultrasound ... output causes increases ... Tolerance #testing #diagnosis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
nose deformity • Cardiac ... (UPC) ratio • Cardiac ... o infection • Echocardiogram ... recent DAN) • EMG ... Goodpasture's cause
Peripartum Cardiomyopathy - Summary 1. Definition • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... LVEDd > 6.0 cm, LV thrombus ... and timing with Cardio-OB ... Serial TTE and close ... follow-up with Cardio-OB
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