42 results
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
AIHA (48-70%) Cold ... HA (paroxysmal cold ... hemoglobinuria) • Cold ... Agglutinin Disease ... #Table #hematology
COPD assessment and classification as proposed by GOLD 2001, 2006, 2011 and 2017 Reports. For further
COPD assessment ... mMRC: modified Medical ... Council; CAT: COPD ... #Diagnosis #Pulmonary ... #COPD #Assessment
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... #differential #diagnosis ... #hematology #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
- Differential Diagnosis ... Algorithm Extravascular ... Warm AIHA • Cold ... Complement-Mediated • Cold ... #Hematology
GOLD2017 - The refined ABCD assessment tool. FEV1: forced expiratory volume in 1 s; FVC: forced vital
Obstructive Lung Disease ... mMRC: modified Medical ... Council; CAT: COPD ... #Diagnosis #Pulmonary ... #COPD #GOLD2017
Pulmonary Function Testing (PFT) Interpretation Algorithm

Restrictive Lung Disease:
 • Chest wall or neuromuscular disorders
 • Interstitial
Pulmonary Function ... Emphysematous COPD ... Non-emphysematous COPD ... #diagnosis #asthma ... #COPD
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin ... Cold Agglutinins ... Viral Infection Clinical ... Diagnosis: • hemolytic ... #hematology #diagnosis
Pulmonary Function Tests (PFTs) - Interpretation Algorithm
 • Normal
 • Pulmonary Hypertension, Anemia, Carboxyhemoglobinemia
 • Chest
Interpretation Algorithm ... Interstitial Lung Disease ... Non-Emphysematous COPD ... Emphysematous COPD ... #diagnosis
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
in Autoimmune Hemolysis ... , C3d ( +/- ) Cold ... agglutinin disease ... ) Paroxysmal cold ... #hematology #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... Agglutination - Cold ... #Algorithm #workup ... #hematology #testing