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management hematology lupus syndrome differential erythematosus signs symptoms dermatomyositis oncology vasculitis activation antimda5 antimda5dm antinxp2 antinxp2dm arteritis autoimmune behcet bleeding
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 100,000, Typically Age ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Management #Summary #rheumatology
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
characterized by a systemic ... Skin rash and malaise ... The signs and symptoms ... reddish brown spots ... #Diagnosis #Clinical
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... 3rd Decade Skin ... Differential Diagnosis ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... months to years) Systemic ... 100,000, Typically Age ... comparison #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... erythematosus [SLE ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
mucositis - Rash ... Takayasu: - Age ... purpura: strong sign ... vasculitis, and SLE ... #rheumatology #
Kussmaul's Sign and Friedreich's Sign on Neck Examination A middle-aged M with unknown PMH presents with dyspnea.
Examination A middle-aged ... Most likely diagnosis ... small blue-colored spot ... on the skin (middle ... #PhysicalExam #Clinical
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 Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... to 40 years of age ... Medium and large ... #management #signs ... #symptoms #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... auricular papules Clinical ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
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