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management antibiotics infant pediatrics stepbystep stratification brain clinical cryptococcal differentiation ebm emergencies hematology hemeonc meningitis mri oncologic radiology syndrome t2
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... CRP < 20 mg/L #Diagnosis ... Management #Pediatrics #Peds ... #Febrile #Infant ... #LP #Antibiotics
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Induce blast cell ... Attempt if high risk ... Subacute-Acute: • Common: fever ... Rare: DAH, acute febrile ... #hematology #oncology
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
empiric antibiotic treatment ... 92.0% and 46.9% #Diagnosis ... Management #Pediatrics #Peds ... #LP #Antibiotics ... #Fever
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
work-up - If febrile ... mg/dL or > 25 % rise ... interventional radiology ... ± tocilizumab; call ... #HemeOnc #Diagnosis
Cryptococcal meningitis on T2 MRI 30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
Diagnosis? ... are common but fever ... half. absence of fever ... Standard treatment ... If a second LP is
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