3524 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Immune Complex Mediated ... ) Pauci-immune mediated
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
entirely T-Cell mediated ... exposure to allergen causes ... Allergy #Immunology #pathophysiology
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare but potentially serious adverse reaction that has been
The exact cause ... is known to be mediated ... antibodies which cause ... thrombocytopenia #COVID #pathophysiology
Hemolysis in Hereditary Spherocytosis. Panel A shows the structure of a normal red cell and a
and cytoskeleton mediated ... deficiencies that cause ... #Pathophysiology
Pathogenesis of Rheumatic Fever

Pathogenesis of rheumatic fever. 
1. GAS pharyngitis leads to antigenic presentation of pathogenic
leading to cytokine-mediated ... antibodies which can cause ... Rheumatic #Fever #Pathophysiology
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
Sclerosis -> Immune-mediated ... Manic #Secondary #Causes ... Differential #Diagnosis #Pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... • T lymphocyte mediated ... intralobular bile ducts causes
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
: • 1400 new cases ... monophasic Pathophysiology ... super-antigen mediated ... disease • Immune Mediated ... • Infectious causes
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Anemia (AIHA) Pathophysiology ... AIHA: - 70%; IgG mediated ... AIHA: - 20%; IgM mediated ... Hemolytic #Anemia #Pathophysiology
Hypercalcemia of Malignancy - Pathophysiology
PTH-mediated
 • Parathyroid cancer
 • Ectopic production: Small cell lung cancer, ovarian
of Malignancy - Pathophysiology ... PTH-mediated ... thyroid Vitamin D mediated ... Lymphomas PTHrp Mediated ... Hypercalcemia #Malignancy #Pathophysiology