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management differential hematology oncology vasculitis anemia aplastic apml barre behcet cardiology clinical criticalcare differentiation disease encephalopathy endocrinology foamed gbs guillain
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
21 • Noonan Syndrome ... • Prader-Willi Syndrome ... Russell-Silver Syndrome ... • Turner Syndrome ... Cystic Fibrosis, CHF
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... rasburicase Tumor Lysis Syndrome ... #Tumor #Lysis #Syndrome ... #management #hematology
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Refeeding Syndrome ... decompensation (CHF ... Epilepsy • Fanconi syndrome ... • Nephrotic syndrome ... #Refeeding #Syndrome
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Encephalopathy Syndrome ... Clinico-Radiological Syndrome ... syndrome by 24 ... Paraneoplastic syndrome ... Encephalopathy #Syndrome
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Pathophysiology ... : >3 symptoms, or ... Differentiation #Syndrome ... #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... age 70 years Symptoms ... (CML) • Felty Syndrome ... #diagnosis #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... occlusion, Budd-Chiari syndrome ... tests in Behcet syndrome ... adenopathy (PFAPA) syndrome ... #signs #symptoms
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome ... Anemia #oncology #hematology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
Deficiency in galactosylation ... nephrotic/nephritic syndrome ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... than one after symptom ... and cauda equina TREATMENT ... Guillain #Barre #Syndrome ... #neurology
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