10 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Localization of Renal ... Tubular Defects ... loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... Pathophysiology #Nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... Epithelial Cells Renal ... ascending limb Gitelman ... receptor Distal renal ... #Kidney #Nephrology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Inappropriate renal ... Inappropriate renal ... kidney disease Renal ... #Workup #nephrology
Pharmacological Treatment of Hepatorenal Syndrome (HRS)

Midodrine - Alpha agonist incr blood pressure incr renal perfusion pressure
of Hepatorenal Syndrome ... pressure incr renal ... edgarvlermamd - Nephrology ... #Nephrology #Management ... #Pharmacology #
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... cotransporter • Gitelman's ... • Hypokalemia (renal ... , Renal tubular ... #nephrology #management
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
diuretics after renal ... generally indicates a renal ... tubule reabsorptive defect ... furosemide-like lesion) • Gitelman ... Diagnosis #Causes #nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
HYPOTENSION → renal ... vasoconstriction → decreased renal ... perfusion → renal ... Cast formation: Renal ... causes #treatment #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... Inhibitors of Renal ... #Diuretics #Renal ... Excretion #Diuresis #Nephrology ... #Pharmacology #
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Immunosuppressive agents, Renal ... Neurological symptoms ... #diagnosis #management ... #neurology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Afferent pupillary defect ... objective evidence of neurologic ... sclerosis #diagnosis #management ... #neurology #treatment