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Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
• Uric

Uric acid ≥ 8.0 mg ... /dL • Potassium ... ≥ 6.0 mEq/dL ... Phosphorus ≥ 4.6 mg ... ≤ 7.0 mg/dL Clinical

Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
• Onset/Trimester: 25-32 weeks
• Typical clinical features:

weeks • Typical clinical ... Bilirubin: <5 mg ... /dL • Hepatic ... Bilirubin: <5 mg ... /dL unless massive

Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider

Uric acid ≥ 8 mg ... /dL • Potassium ... /dL • Calcium ... ≤ 7 mg/dL • OR ... Treatment of Clinical

Vertical (Upbeat) Nystagmus on Physical Exam

This patient had severe hypomagnesemia. Serum Mg 0.1 mg/dl.

Dr. Arvind Canchi

Serum Mg 0.1 mg/ ... dl. ... hypomagnesemia #clinical

Muehrcke's Lines (Leukonychia striata)
Narrow while transverse lines (Not depressed, compared to Beau's lines). Usually 2 or

less than < 2.2 g/dL ... #PhysicalExam #Clinical ... #Photo #Sign

Herpes Zoster Mandibularis - The lesions were scattered along the area that is innervated by the

#Clinical #Photo ... Mandibularis #Rash #NEJM

A necrotic ulceration was observed on the right side of the tongue. Cervicofacial computed tomography, performed

giant-cell arteritis #clinical ... #photo #lingual ... Arteritis #tongue #NEJM

$Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population$

as jaundice on clinical ... than 20 to 50 mg ... /dL. ... ranging from 7-20 mg ... /dL • CN syndrome

Radial Fracture Due to Parathyroid Carcinoma- ...A plain radiograph of the left arm showed a diaphyseal

level of 13.0 mg ... range, 8.5 to 10.2 mg ... level was 9.0 mg ... #clinical #radiology ... #NEJM #parathyroid

Clinical diagnosis of Alcoholic Hepatitis (AH)
• Onset of jaundice within prior 8 weeks
• Ongoing

Clinical diagnosis ... bilirubin >3.0 mg ... /dL Potential confounding

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