1098 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... Uric acid ≥ 8.0 mg ... ≤ 7.0 mg/dL Clinical ... #TumorLysis #Syndrome ... #TLS #diagnosis
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... Uric acid ≥ 8 mg ... ≤ 7 mg/dL • OR ... #Tumor #Lysis #Syndrome ... #diagnosis #management
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
- calcium > 11 mg ... /dL / >1 mg/dL the ... disease - Cr >2 mg ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis
Gestational Hypertension & Preeclampsia

Gestational Hypertension (gHTN) 
• BP > 140/90 
• Onset > 20 wks gestation
Proteinuria (300 mg ... ) • Cr > 1.1 mg ... /dL or 2x • Thrombocytopenia ... Seizure HELLP Syndrome ... Classification #Diagnosis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Bilirubin: <5 mg ... /dL • Hepatic ... necrosis HELLP Syndrome ... Bilirubin: <5 mg ... #differential #diagnosis
Albuminuria (Grades) and Risk for CKD
Normal to mildly increased albuminuria:
 - Albumin excretion rate: < 30
excretion rate: < 30 mg ... ratio: 30-300 mg ... hypoalbuminemia (<3.0 g/dL ... defined as nephrotic syndrome ... CKD #nephrology #diagnosis
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
than 20 to 50 mg ... /dL. ... ranging from 7-20 mg ... /dL • CN syndrome ... bilirubin #hepatology #diagnosis
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Hepatorenal Syndrome ... (HRS) - Diagnostic ... Creatinine by 0.3 mg ... /dL (27 μmol/L) ... #diagnosis #HRSAKI
Hypertensive Disorders of Pregnancy
Chronic Hypertension:
 • Guidelines as SBP ≥130 or DBP ≥ 90 mmHg
 •
• First diagnosed ... Proteinuria (e.g., 300 mg ... insufficiency (Cr > 1.1 mg ... /dL or doubling ... patients • HELLP: Syndrome
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
factor PRES Diagnosis ... Differential Diagnosis ... level (mean 58 mg ... /dL in one study ... #diagnosis #management