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diagnosis nephrology ckd algorithm pharmacology differential management pathophysiology causes diabetes renal albuminuria metformin nejm treatment classification complications dosing endocrinology gfr
ALBUMINURIA • Indicator of kidney damage and / or a biomarker of systemic diseases dates back to 1969,
formerly called "microalbuminuria ... independent of eGFR ... cardiovascular #eGFR ... #AER #ACR #macroalbuminuria ... #microalbuminuria
The GFR Clock for Staging CKD Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... function rate (eGFR ... calculating the eGFR ... to remember the eGFR ... #Nephro #CKD #EGFR
Albuminuria (Grades) and Risk for CKD Normal to mildly increased albuminuria: - Albumin excretion rate: < 30
albuminuria (formerly Microalbuminuria ... albuminuria (formerly Macroalbuminuria ... - Macroalbuminuria
Interpreting Kidney Biomarkers ↑ Creatinine: • AKI, CKD • Medications that lead to nephroprotective ↓ in
nephroprotective ↓ in GFR ... hyperthyroidism ↓ eGFR
Renal Failure Prognosis - The eGFR and proteinuria offers a general prognosis as demonstrated in the
Prognosis - The eGFR ... #CKD #EGFR #Proteinuria
To improve the usefulness of the serum creatinine concentration as a marker of kidney function, prediction
accurately predict GFR ... overestimation of GFR ... used to estimate GFR ... CockcroftGault #EGFR
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 Causes of Hypomagnesemia - Differential Diagnosis Algorithm GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Cetuximab and other EGFR ... in Na-KATPase, EGFR
Metformin in Diabetic Kidney Disease Immediate release: • Initial 500 mg or 850 mg once daily •
maximum dose eGFR ... recommended dose eGFR
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
- 85% • Mean eGFR ... follow-up • eGFR
Metformin Current Renal Dose Adjustments due to Risk of Lactic Acidosis > 60 No adjustment 45-60
45-60 Monitor eGFR
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