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rheumatology management erythematosus systemic druginduced neurology treatment activation algorithm antiphospholipid apls arthritis bcnie bloodculture cerebritis classification cns comparison cryofibrinogenemia cryoglobulinemia
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... Positive in 60-80% of cases ... Erythematosus #Diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... • Immunologic Workup ... #table #rheumatology ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Differential Diagnosis ... . hematologic) ... Clinical Features
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... erythematosus [SLE ... #Diagnosis #Management ... #Hematology #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... : • Clinical triad ... Labs/Diagnosis: ... . systemic lupus
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... /Cranial nerve pathology ... myasthenia Diagnosis ... and EMG Findings ... Myasthenia #Gravis #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... (to support a diagnosis ... ANA and RF (if clinical ... #diagnosis #testing
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
antimicrobials, clinical ... but important causes ... BCNIE Diagnostic ... See charts - ... antiphospholipid syndrome
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... cryoglobulins • Negative causes ... Biopsy: Typical pathologic ... Antiphospholipid syndrome ... hematology
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