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differential anemia causes dermatology basics bloodcell cell electrophoresis eosinophil eosinophilia fractures fragility hemolytic indications key macrocytic microcytic microscopy msk oncology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Unstable hemoglobin disorders ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... evaluation or workup ... signs or symptoms (eg ... #diagnosis #hematology
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm Tumours - See Bone Lesions Scheme Paget's Disease -
Pathologic / Fragility ... - Differential Diagnosis ... Algorithm Tumours ... - See Bone Lesions ... • Bone Marrow Disorder
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
a generalized disorder ... nettle sting #Diagnosis ... #Dermatology #Skin ... #Terminology #Nomenclature ... #Atlas #Key #Basics
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Algorithm • Sickle ... other reproducible morphologic ... Consider RBC membrane disorder ... #Algorithm #workup ... #hematology #testing
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (BM) ablative disorders ... of substrate (e.g ... #Diagnosis #Workup ... #Hematology #Microcytic
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... reddish-purple lesions ... Vasculitis - Collagen disorders ... deficiency Work
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
amyloidosis, or related disorder ... • Unexplained pathologic ... fracture or lyric lesion ... Electrophoresis #SPEP #Hematology ... #Diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
red bone marrow, e.g ... Diagnosis? ... Biopsy: Solitary disorder ... IFE, FLC assay Pathology ... #Workup #Hematology
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