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differential algorithm rheumatology causes hemolytic microscopy protein testing approach bloodcell cell chronic disease electrophoresis erythematosus fatigue gap globulin indications joint
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Unstable hemoglobin disorders ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... and laboratory diagnosis ... , not a morphologic ... count, D-dimer, egg ... #Hematology #Pathology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... changes), high MCV anemia ... #Causes #Workup ... #hematology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Enthesitis: • Site of pathology ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis ... #arthritis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... other reproducible morphologic ... Consider RBC membrane disorder ... #Algorithm #workup ... #hematology #testing
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (BM) ablative disorders ... of substrate (e.g ... #Algorithm #Diagnosis ... #Workup #Hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • Anemia • ... • Rheumatoid Arthritis ... • Drug Abuse (e.g ... • Somatization Disorder
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... metabolic or endocrine disorders ... #laboratory #workup ... #diagnosis #testing
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... . hematologic) ... • Endocrine disorders ... lymphopenia, low PLT • Anemia ... Erythematosus #Diagnosis
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
amyloidosis, or related disorder ... • New-onset anemia ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology ... #Diagnosis
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