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arthritis differential rheumatology joint msk bloodcell cell disease electrophoresis indications laboratory microscopy monoarthritis monoarticular nomenclature oligoarthritis oligoarticular oncology plasmacytoma polyarthritis
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Approach to Joint ... Enthesitis: • Site of pathology ... #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Unstable hemoglobin disorders ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Approach to Joint ... Differential Diagnosis ... Mechanical/degenerative disorders ... tuberculosis) • Fungi ... #MSK #rheumatology
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
amyloidosis, or related disorder ... possible malignancy (e.g ... • Unexplained pathologic ... Electrophoresis #SPEP #Hematology ... #Diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... metabolic or endocrine disorders ... , and low back pain ... (to support a diagnosis ... #diagnosis #testing
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
presents with pain ... red bone marrow, e.g ... Biopsy: Solitary disorder ... IFE, FLC assay Pathology ... #Workup #Hematology
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