10 results
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... Cell (RBC) Morphologies ... #RedBloodCell #Morphology ... Morphologies #Key #Atlas ... #Hematology #Diagnosis
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... Chemotherapy (e.g ... Unstable hemoglobin disorders ... #diagnosis #hematology ... #microscopy #atlas
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (BM) ablative disorders ... of substrate (e.g ... Anemia #Algorithm #Diagnosis ... #Workup #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... function test, ANA (e.g ... #Causes #Workup ... #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... other reproducible morphologic ... membrane disorder ... #Algorithm #workup ... #hematology #testing
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
Approach to the ... • Provoked (e.g ... - No other workup ... cancer screening, CBC ... #hematology #diagnosis
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Approach to Joint ... Enthesitis: • Site of pathology ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Approach to Joint ... Arthritis Differential Diagnosis ... , erythema and WBC ... Mechanical/degenerative disorders ... tuberculosis) • Fungi
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... metabolic or endocrine disorders ... (to support a diagnosis ... Arthritis #laboratory #workup ... #diagnosis #testing
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
red bone marrow, e.g ... Biopsy: Solitary disorder ... • CBC + diff • ... IFE, FLC assay Pathology ... #Workup #Hematology