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differential rheumatology management algorithm approach bloodcell cell dermatology disease eosinophil eosinophilia gammopathy gravis joint laboratory mgrs microscopy monoclonal msk myasthenia
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Enthesitis: • Site of pathology ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis ... #arthritis
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... glucocorticoid treatment ... signs or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Unstable hemoglobin disorders ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
an autoimmune disorder ... syndrome, rheumatoid arthritis ... /Cranial nerve pathology ... myasthenia Diagnosis ... Serologic and EMG
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... metabolic or endocrine disorders ... (to support a diagnosis ... #laboratory #workup ... #diagnosis #testing
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... nonerosive inflammatory arthritis ... and lower jaw Treatment ... antiinflammatory properties e.g
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
or plasma cell disorder ... light-chain ratio Diagnostic ... Workup: • Kidney ... microangiopathy Treatment ... #Significance #Diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
red bone marrow, e.g ... Biopsy: Solitary disorder ... IFE, FLC assay Pathology ... Bone marrow Treatment ... #Workup #Hematology
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