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differential causes anemia macrocytic oncology rheumatology systemic testing arthritis blood bloodcell cll daytime dermatology disease elevatedmcv erythematosus essential et excessive
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... Chemotherapy (e.g ... Unstable hemoglobin disorders ... #diagnosis #hematology ... #microscopy #atlas
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm Insufficient Sleep • Poor Sleep Hygiene • Insomnia
- Differential Diagnosis ... Algorithm Insufficient ... Shift Work) Sleep ... Restless Legs Syndrome ... Excessive #Daytime #Fatigue
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... T-cell - CD7, CD3 Chronic ... - Abnormal morphology ... bcr-able (+) ↑ WBC ... #hematology #Markers
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • Drug Abuse (e.g ... • Somatization Disorder ... Fatigue Syndrome ... #Chronic #Fatigue
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (BM) ablative disorders ... of substrate (e.g ... #Diagnosis #Workup ... #Hematology #Microcytic
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Algorithm • Sickle ... other reproducible morphologic ... membrane disorder ... #Algorithm #workup ... #hematology #testing
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... sweats • Extreme fatigue ... lymphoproliferative disorders ... #workup #oncology ... #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... discoloration) • Chronic ... • Nephrotic syndrome ... #Differential #Diagnosis ... #Algorithm #causes
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Clinical evidence of (fatigue ... Differential Diagnosis ... . hematologic) ... with Lupus: • Chronic ... Erythematosus #Diagnosis
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