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differential causes rheumatology algorithm dermatology management systemic erythematosus nomenclature oncology sle acquired activation allergy alopecia amenorrhea amyloid amyloidosis anemia arthritis
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
inflammatory disorders ... (e.g. autoimmune ... Myelodysplastic syndrome ... #Causes #hematology ... #secondary
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Headache, Movement disorders ... , Seizure disorders ... Lumbar Puncture, EEG ... APS), Secondary
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Unstable hemoglobin disorders ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... • Screen for secondary ... signs or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... . lupus, CLL, lymphoma ... lymphoproliferative disorders ... #hematology #anemia
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... halt nail growth (e.g ... discoloration) • Chronic ... • Nephrotic syndrome ... #Diagnosis #Algorithm
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Type III Often Secondary ... Labs/Diagnosis: ... (e.g. systemic ... lupus erythematosus ... Cryoglobulins #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... . hematologic) ... • Endocrine disorders ... : • Chronic B-cell ... Erythematosus #Diagnosis
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
- Differential Diagnosis ... Neoplastic / Hematologic ... • Drug Abuse (e.g ... • Somatization Disorder ... Fatigue Syndrome
Causes of Secondary Amenorrhea - Differential Diagnosis Algorithm Absence of menses for more than 3 cycles or
Causes of Secondary ... - Differential Diagnosis ... normal prolactin, chaotic ... . eating disorder ... #Differential #Diagnosis
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