30 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Secondary ... disordersDiagnosis ... #HES #Hematology ... #eosinophils #diagnosis ... #management #algorithm
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
inflammatory disorders ... (e.g. autoimmune ... Myelodysplastic syndrome ... #Causes #hematology ... #secondary
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... - Diagnosis and ... Management • ... #Diagnosis #Management ... #treatment #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Unstable hemoglobin disorders ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... • Screen for secondary ... signs or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... halt nail growth (e.g ... discoloration) • Chronic ... • Nephrotic syndrome ... #Diagnosis #Algorithm
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... , Seizure disorders ... Lumbar Puncture, EEG ... APS), Secondary ... #management #treatment
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
- Differential Diagnosis ... Neoplastic / Hematologic ... • Drug Abuse (e.g ... • Somatization Disorder ... Fatigue Syndrome
Causes of Secondary Amenorrhea - Differential Diagnosis Algorithm
Absence of menses for more than 3 cycles or
Causes of Secondary ... - Differential Diagnosis ... normal prolactin, chaotic ... . eating disorder ... #Differential #Diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Type III Often Secondary ... Labs/Diagnosis: ... (e.g. systemic ... Cryoglobulins #diagnosis ... classification #rheumatology