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differential hematology neurology treatment algorithm rheumatology cardiology barre endocarditis guillain secondary systemic abscess activation bloodcell cerebritis chf clinical cns crisis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Blood Cell (RBC) Morphology ... Chemotherapy (e.g ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... #hematology #anemia
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... inflammatory disorders (e.g ... Myelodysplastic syndrome ... #Causes #hematology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia Focal Hyporeflexia: • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
polyneuropathy (e.g ... Guillain-Barré syndrome ... Hyperthyroidism, Serotonin syndrome ... #differential #diagnosis ... #table #neurology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Hematology
Hypermagnesemia - Etiologies by Mechanism Renal Failure Excessive Mg Administration - Massive PO intake
IV Mg infusion (e.g ... - Tumor lysis syndrome ... #Differential #Diagnosis ... High #Magnesium #Table ... #Causes #Management
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
halt nail growth (e.g ... • Nephrotic syndrome ... Systemic #Secondary #dermatology ... #Differential #Diagnosis ... #Algorithm #causes
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
and Management ... and pernicious anemia ... unit activity on EMG ... of diazepam • EMG ... TPO, TTG, etc EMG
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
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