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differential dermatology abnormal anemia aptt hemolytic nomenclature pathology prolonged pt rbc skin algorithm autoimmune basics bleeding bloodcell bloodsmear bruising classification
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
#RedBloodCell #Morphology ... #Morphologies #Key ... #Atlas #Microscopy ... #Pathology #Hematology ... #Diagnosis #Dyspmorphic
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
and laboratory diagnosis ... , not a morphologic ... intravascular coagulation ... count, D-dimer, egg ... hemolytic #anemia #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Rare • Drugs (e.g ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... (usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... #hematology #anemia
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
to one factor e.g ... e.g. heparin ... inhibitory drugs e.g ... #diagnosis #differential ... #hematology #coagulation
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Blood Cell (RBC) Morphology ... Chemotherapy (e.g ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... (e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #hematology #coagulation
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
altered colour e.g ... nipple-like mass e.g ... nettle sting #Diagnosis ... #Nomenclature #Atlas ... #Key #Basics
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... vasculitis - GPA, EGPA, microscopic ... tissue disorder (e.g ... classification #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
skeleton-sacroiliac joint and spine ... Rule out other causes ... antiinflammatory properties e.g ... SAPHO #Syndrome #Rheumatology ... #Dermatology
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