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management differential nephrology treatment renal infectiousdiseases syndrome syndromes urine acute aki aptt arteritis aspergillus bloodcell coagulation common crisis dermatology disorders
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... • White cell casts ... casts - Any type ... #Atlas #key #diagnosis
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... Casts • Hyaline ... colored compounds (e.g ... #Urine #Microscopy ... interpretation #diagnosis
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
dialysis indication (e.g ... Nephrotoxic drugs (e.g ... PROBLEM ~80% of AKI cases ... Assess UA w/ microscopy ... for WBCs, RBCs, casts
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... PLT in selected cases ... function test, ANA (e.g ... #Causes #Workup
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Blood Cell (RBC) Morphology ... Chemotherapy (e.g ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... to one factor e.g ... e.g. heparin ... inhibitory drugs e.g ... #diagnosis #differential
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
study (aPTT may be normal ... in mild cases) ... antigen (vWF:Ag) are normal ... hemophilia type (e.g ... Management #treatment #hematology
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
infections are caused ... immunosuppression (eg ... Non-pigmented (hyaline ... sometimes have this morphology ... considered in certain cases
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA (microscopic ... mononeuritis multiplex WORKUP ... recent DAN) • EMG ... Goodpasture's cause ... hematuria, RBC casts
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age • 22 and 45 cases ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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